Research Roundup: Musculoskeletal

The latest research in CTDs and Musculoskeletal Conditions, listed from most recent (top of list) to older resources (bottom of list).

Listings include a link embedded in the name of the study, the year it was published, and a credit to the group member who shared it with us.

What looks like a serious x-ray is actually a playful skeleton holding a camera, ready to take your picture

Long COVID symptoms lead to hEDS diagnosis in small study, …the presence of SARS-CoV-2 itself may trigger a misdirected host immune response to traumatized connective tissue in such patients with preexisting joint hypermobility and may yet represent another possible mechanism for new-onset or worsening connective tissue symptoms within the post-acute infection period. by Patricia Inácio, PhD for Ehlers-Danlos News, January 2024

Epilepsy drug shows promise in slowing joint degeneration in osteoarthritis, a drug target that may alleviate the joint breakdown, by Bill Hathaway for YaleNews, January 2024, via Jane Y.

Spinal fusion carries greater risk of complications for EDS patients, 6 times higher risk of degeneration of unfused bones next to fusion site: Study. Steve Bryson for Ehlers-Danlos News, December 2023

Novel Blood Test Can Detect Rheumatoid Arthritis, Randy Dotinga for Medscape, November 2023

Bone Degradation Measure Can Sway Osteoporosis Diagnosis, Jake Remaly for Medscape, October 2023.

Pediatric joint hypermobility: a diagnostic framework and narrative review, Orphanet Journal of Rare Disease, May 2023

Axial Spondyloarthritis vs Axial Psoriatic Arthritis: Different Entities? by Neil Osterwell for Medscape May 2023

Presentation and physical therapy management of upper cervical instability in patients with symptomatic generalized joint hypermobility: International expert consensus recommendations, Frontier Medicine /Translational Medicine, January 2023 via Karina S.

Scientists discover possible target for treating and preventing osteoarthritis, UF Health, October 2022 via Jane Y.

Augmented reality: A new tool for knee replacement , Mayo Clinic’s Q&A Audio Library, August 2022

Hopkins team reaches finals of Collegiate Inventors Competition for developing “The Dynamic Brace”, a brace for children born with clubfoot. September 2022 via Jon R.

Orthapedic Management of the Ehlers-Danlos Syndromes 2017 via PGD

Muscle mass, muscle strength, functional performance, and physical impairment in women with the hypermobility type of Ehlers-Danlos Syndrome 2012 via PGD

Mice deficient in small leucine-rich proteoglycans: novel in vivo models for osteoporosis, osteoarthritis, Ehlers-Danlos syndrome, muscular dystrophy, and corneal diseases 2002 via PGD

Phenotypic effects of biglycan deficiency are linked to collagen fibril abnormalities, are synergized by decorin deficiency, and mimic Ehlers-Danlos-like changes in bone and other connective tissues 2002 via PGD

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